Glutathione 1500mg

Description

Glutathione 1500mg – High-Potency Cellular Redox & Detoxification Standard

Buy Glutathione in Canada – High-Purity Reference Standard for Thiol Dynamics & Oxidative Stress Research

Glutathione ($\gamma$-L-glutamyl-L-cysteinylglycine / GSH) is a vital tripeptide featuring an atypical isopeptide linkage between the glutamate side-chain carboxyl and the cysteine amino group, protecting it from degradation by standard cellular peptidases. Operating at the core of cellular defense mechanisms, the active free thiol (-SH) on the cysteine residue acts as a direct electron donor, reducing reactive oxygen species, hydroxyl radicals, and lipid hydroperoxides. In analytical and cellular models, Glutathione functions as an obligate substrate for glutathione peroxidase (GPx) and glutathione S-transferases (GSTs), facilitating electrophilic xenobiotic conjugation and enzymatic Phase II clearance pathways. Furthermore, maintaining an optimal reduced-to-oxidized ratio ($\text{GSH}/\text{GSSG}$) is fundamental to cellular signaling, NF-$\kappa$B pathway modulation, and the prevention of mitochondrial permeability transition pore opening. For Canadian academic institutions and analytical facilities investigating cellular cytoprotection, thiol-disulfide exchange kinetics, and hepatocyte detoxification pathways, North Vital Labs supplies analytical-grade Glutathione 1500mg backed by comprehensive third-party testing.

Primary Research Applications

• Redox Homeostasis & Thiol Kinetics: Serves as a primary reference standard for measuring intracellular $\text{GSH}/\text{GSSG}$ ratios, mitochondrial membrane potential preservation, and cellular oxidative buffering capacity.

• Phase II Detoxification Pathways: Facilitates laboratory evaluation of glutathione S-transferase (GST) conjugation dynamics and xenobiotic metabolism in hepatic cell assays.

• Enzymatic Radical Scavenging: Widely utilized to assess the activity and kinetics of glutathione peroxidase (GPx) and glutathione reductase (GR) cascades under targeted chemical oxidation stress.

• Cellular Melanogenesis Modulation: Enables in vitro observation of tyrosinase enzyme activity suppression and pathway shifting from dark eumelanin synthesis toward lighter pheomelanin production in melanocyte models.

Why Canadian Researchers Choose North Vital Labs

• 100% Domestic Canadian Fulfillment: Direct domestic transit ensures zero border delays, unexpected customs tariffs, or import inspection risks.

• HPLC Lab-Verified Purity: Each lot undergoes rigorous third-party testing to guarantee 99%+ chemical purity, accompanied by verifiable Certificates of Analysis (COAs).

• Direct Domestic Checkout: Seamless and reliable ordering supported by standard Canadian payment options, including Interac e-Transfer.

• Discreet Express Delivery: Shipped across Canada in protective, oxidation-resistant, temperature-stable packaging with live tracking provided upon dispatch.

Compound Specifications

• Molecular Name: L-Glutathione (Reduced / $\gamma$-L-Glutamyl-L-cysteinylglycine)

• Potency / Quantity: 1500mg per vial

• Form: Lyophilized white powder (freeze-dried cake)

• Purity: 99%+ (HPLC lab-verified)

• Storage Protocol: Store lyophilized powder in a cool, dry place away from direct light (refrigerate at 2°C–8°C once reconstituted; keep sealed to minimize thiol auto-oxidation).

• Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, clinical, or veterinary use. This compound has not been evaluated or approved by Health Canada.