Description
MOTS-c – Advanced Mitochondrial-Derived Research Peptide
Buy MOTS-c in Canada – High-Purity Standard for AMPK Activation & Metabolic Signaling Research
MOTS-c is an endogenously identified mitochondrial-encoded peptide recognized for its central role in mediating retrograde mitonuclear communication. Rather than being confined to the organelle, MOTS-c responds to metabolic and exercise-induced stress by translocating into the cell nucleus, where it coordinates the expression of adaptive antioxidant and energy-regulating genes. For Canadian researchers and analytical laboratories studying glucose disposal kinetics, cellular senescence, and mitochondrial adaptation, North Vital Labs supplies analytical-grade MOTS-c backed by comprehensive laboratory verification.
Primary Research Applications
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AMPK Pathway Activation: Serves as a benchmark reference standard for studying the Folate-AICAR-AMPK axis, cellular fuel sensing, and fatty acid oxidation mechanisms.
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Glucose Disposal & Insulin Signaling: Facilitates the investigation of non-incretin insulin-sensitizing pathways, GLUT4 transporter translocation, and skeletal muscle glucose uptake.
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Exercise Mimetic Signaling: Utilized in metabolic models to evaluate cellular adaptations analogous to high-intensity aerobic training and physical exertion.
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Mitonuclear Retrograde Communication: Enables laboratory observation of nuclear translocation events, antioxidant response element (ARE) binding, and systemic cellular stress adaptation.
Why Canadian Researchers Choose North Vital Labs
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100% Domestic Canadian Fulfillment: Shipments originate directly within Canada, guaranteeing no international border clearance delays, unexpected customs fees, or regulatory seizures.
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HPLC Lab-Verified Purity: Each production lot undergoes independent analytical testing to guarantee 99%+ chemical purity, accompanied by verifiable Certificates of Analysis (COAs).
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Direct Domestic Checkout: Seamless ordering supported by established Canadian payment systems, including Interac e-Transfer.
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Discreet Express Delivery: Shipped across Canada in protective, temperature-stable packaging with real-time tracking provided upon dispatch.
Compound Specifications
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Molecular Name: MOTS-c (Mitochondrial ORF of 12S rRNA-c / 16-AA Peptide)
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Form: Lyophilized white powder (freeze-dried cake)
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Purity: 99%+ (HPLC lab-verified)
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Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).
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Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, clinical, or veterinary applications. This compound has not been evaluated or approved by Health Canada.
“Honestly was a bit skeptical at first ordering online, but the stuff arrived in 3 days with solid tracking. Dissolved clean with zero cloudiness. Legit quality and will definitely be reordering.”
Prince George, BC
“Paid with e-transfer and got the shipping notification the same afternoon. Packaging was completely plain which I appreciated. The product is working exactly as expected in my routine. 10/10.”
Caledon, Ontario
“Great experience overall. The Reta itself seems super high grade. Took one extra day to get out to Calgary because of a weekend, but support was quick to reply to my email.”
Calgary, Alberta
“Nobody sells this locally and every other site charges out the a**. Found these guys, paid with e-transfer, and had the product at my door in 2 days. Dissolved clean and didn’t get killed on price. Definitely ordering again.”
Vancouver, BC







