Description
VIP (Vasoactive Intestinal Peptide) | 5 mg
Class: Regulatory Neuropeptide / Glucagon-Secretin Superfamily
VIP is an endogenous 28-amino acid regulatory polypeptide distributed across central and peripheral nervous system networks, lymphoid tissue, and the gastrointestinal tract. Acting via high-affinity G-protein-coupled VPAC1 and VPAC2 receptors, VIP orchestrates cellular immune homeostasis, dampens microglial activation, and stimulates vascular smooth muscle relaxation. It is widely investigated in protocols exploring neuro-immune dysfunction, Chronic Inflammatory Response Syndrome (CIRS), pulmonary arterial hypertension, and mucosal barrier stabilization.
Key Research Findings & Properties
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Cytokine Network Modulation: Downregulates inflammatory signaling cascades, notably attenuating elevations in TNF-$\alpha$, TGF-$\beta$1, MMP-9, and IL-6.
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Microvascular Hemodynamics: Triggers endothelial nitric oxide release to alleviate elevated pulmonary artery pressure and enhance peripheral tissue perfusion.
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Neuroimmune Regulation: Blunts localized central neuroinflammation and facilitates microglial phenotypic switching toward restorative signaling.
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Mucosal & Epithelial Defense: Enhances gastrointestinal and respiratory epithelial junction integrity under toxic or inflammatory stress.
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Treg Stabilization: Supports CD4+ regulatory T-cell differentiation, counterbalancing auto-reactive immune responses in chronic biological challenge models.
“Honestly was a bit skeptical at first ordering online, but the stuff arrived in 3 days with solid tracking. Dissolved clean with zero cloudiness. Legit quality and will definitely be reordering.”
Prince George, BC
“Paid with e-transfer and got the shipping notification the same afternoon. Packaging was completely plain which I appreciated. The product is working exactly as expected in my routine. 10/10.”
Caledon, Ontario
“Great experience overall. The Reta itself seems super high grade. Took one extra day to get out to Calgary because of a weekend, but support was quick to reply to my email.”
Calgary, Alberta
“Nobody sells this locally and every other site charges out the a**. Found these guys, paid with e-transfer, and had the product at my door in 2 days. Dissolved clean and didn’t get killed on price. Definitely ordering again.”
Vancouver, BC
