Description
ARA-290 – Advanced Innate Repair Receptor (IRR) Research Peptide
Buy ARA-290 in Canada – High-Purity Standard for Neuropathy & Tissue Repair Studies
ARA-290 is a specialized synthetic peptide derived from the tissue-protective domain of erythropoietin (helix B). Unlike classic erythropoietic agents, ARA-290 exhibits zero affinity for the homodimeric erythropoietin receptor, completely avoiding hematopoiesis, increased blood viscosity, and pro-thrombotic signaling. Instead, it selectively activates the innate repair receptor (IRR), a heterodimer composed of EPOR and CD131 ($\beta$-common receptor), which triggers rapid anti-inflammatory cascades and promotes peripheral nerve fiber restoration. For Canadian academic laboratories and research facilities investigating neuropathic pain models, microvascular integrity, and systemic inflammatory modulation, North Vital Labs supplies analytical-grade ARA-290 backed by independent laboratory testing.
Primary Research Applications
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Innate Repair Receptor (IRR) Activation: Serves as a standard molecular tool to evaluate EPOR-$\beta$c heteroreceptor downstream protective signaling without affecting red blood cell mass.
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Small Nerve Fiber Repair & Density: Widely utilized to investigate intraepidermal nerve fiber density (IENFD) restoration, axonal regeneration, and Schwann cell survival in peripheral neuropathy models.
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Neuropathic Signaling & Hyperalgesia Modulation: Facilitates the observation of dorsal root ganglion signaling attenuation, allodynia mitigation, and neuroinflammatory pathway downregulation.
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Macrophage Phenotypic Polarization: Evaluates the transition of inflammatory M1 macrophages to reparative M2 phenotypes within compromised microenvironments.
Why Canadian Researchers Choose North Vital Labs
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100% Domestic Canadian Fulfillment: Orders originate directly within Canada, guaranteeing zero customs hold-ups, import tariffs, or border delays.
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HPLC Lab-Verified Purity: Each batch is verified by independent third-party analytical testing to guarantee 99%+ chemical purity, accompanied by accessible Certificates of Analysis (COAs).
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Direct Domestic Checkout: Seamless order processing with standard Canadian payment options, including Interac e-Transfer.
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Discreet Express Delivery: Shipped across Canada in protective, temperature-stable packaging with live tracking provided upon shipment.
Compound Specifications
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Molecular Name: ARA-290 (Cibinetide / Pyroglutamate Helix B Surface Peptide)
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Form: Lyophilized white powder (freeze-dried cake)
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Purity: 99%+ (HPLC lab-verified)
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Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).
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Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, clinical, or veterinary applications. This product has not been evaluated or approved by Health Canada.
“Honestly was a bit skeptical at first ordering online, but the stuff arrived in 3 days with solid tracking. Dissolved clean with zero cloudiness. Legit quality and will definitely be reordering.”
Prince George, BC
“Paid with e-transfer and got the shipping notification the same afternoon. Packaging was completely plain which I appreciated. The product is working exactly as expected in my routine. 10/10.”
Caledon, Ontario
“Great experience overall. The Reta itself seems super high grade. Took one extra day to get out to Calgary because of a weekend, but support was quick to reply to my email.”
Calgary, Alberta
“Nobody sells this locally and every other site charges out the a**. Found these guys, paid with e-transfer, and had the product at my door in 2 days. Dissolved clean and didn’t get killed on price. Definitely ordering again.”
Vancouver, BC
