KPV

KPV

$55.00

KPV (Lysine-Proline-Valine) is a synthetic tripeptide derived from the C-terminal sequence of alpha-melanocyte-stimulating hormone ($\alpha$-MSH), extensively investigated for its anti-inflammatory, antimicrobial, and immunomodulatory activity.

Mechanism & Research Overview

  • Anti-Inflammatory Action: Research indicates KPV acts intracellularly to inhibit the activation and translocation of nuclear factor-kappa B ($\text{NF-}\kappa\text{B}$), significantly attenuating pro-inflammatory cytokine cascades ($\text{TNF-}\alpha$, $\text{IL-}1\beta$, $\text{IL-}6$).

  • Tissue Repair & Wound Modulation: In vitro and in vivo models demonstrate its capacity to accelerate wound healing by reducing local inflammation, mitigating excessive fibrosis, and modulating fibroblast activity during the re-epithelialization phase.

  • Immune Signaling: KPV exhibits host defense modulation without inducing melanogenesis, enabling targeted investigation into inflammatory bowel disease (IBD) models, cutaneous disorders, and localized inflammatory pathways.

Product Specifications

  • Sequence: Lys-Pro-Val

  • Purity: $\ge 99\%$ (independently verified via HPLC & Mass Spectrometry)

  • Form: Lyophilized powder

  • Stability & Storage: Lyophilized material remains stable at room temperature for initial transport. For long-term preservation, store at -20°C in a desiccated, light-protected environment. Once reconstituted, aliquot and store at -80°C; avoid repeated freeze-thaw cycles.

  • Intended Use: For laboratory research use only. Not for human or veterinary diagnostic, therapeutic, or clinical administration. Not evaluated by Health Canada.

SKU: N/A Category: Tags: , , , , Product ID: 7498

Description

KPV – Advanced Anti-Inflammatory & Mucosal Research Peptide

Buy KPV in Canada – Lab-Tested Tripeptide for Scientific Research

KPV is a biologically active tripeptide derived from the C-terminal fragment of alpha-melanocyte-stimulating hormone ($\alpha$-MSH), widely studied in immunological and cellular biology models for its potent anti-inflammatory signaling. Unlike parent melanocortin peptides, KPV exerts strong anti-inflammatory and mucosal-protective properties without inducing melanogenic pigmentary activity. For laboratories and researchers sourcing high-grade KPV in Canada, North Vital Labs delivers pure, analytical-standard compounds backed by independent third-party testing for consistent experimental outcomes.

Primary Research Applications

  • NF-$\kappa$B Signaling Pathway Inhibition: Serves as a primary reference standard for studying nuclear factor-kappa B nuclear translocation and downregulating pro-inflammatory cytokine cascades.

  • Gastrointestinal Barrier & Mucosal Integrity: Investigates cellular tight junction preservation and epithelial tissue protection in intestinal inflammation models.

  • Dermal & Epithelial Regeneration: Evaluates microvascular modulation, fibroblast behavior, and accelerated repair pathways in wound-healing environments.

  • Antimicrobial & Immune Modulation: Enables laboratory analysis of structural defense mechanisms against pathogen colonization without broad immunosuppression.

Why Canadian Researchers Source from North Vital Labs

  • 100% Domestic Canadian Fulfillment: Dispatched directly from within Canada to bypass customs inspections, avoid border delays, and prevent unexpected tariff charges.

  • HPLC Lab-Verified Purity: Every production lot is independently tested to exceed 99% chemical purity, backed by accessible Certificates of Analysis (COAs).

  • Direct Domestic Checkout: Convenient ordering pathways with familiar domestic payment standards, including Interac e-Transfer.

  • Discreet, Express Delivery: Shipped across Canada in protective, temperature-stable packaging with live tracking provided immediately upon fulfillment.

Compound Specifications

  • Molecular Name: KPV (Lysine-Proline-Valine Tripeptide)

  • Form: Lyophilized white powder (freeze-dried cake)

  • Purity: 99%+ (HPLC lab-verified)

  • Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).

  • Compliance Statement: Exclusively intended for laboratory research and analytical development. Not for human, clinical, or veterinary use. This compound has not been evaluated or approved by Health Canada.

 

★★★★★

“Honestly was a bit skeptical at first ordering online, but the stuff arrived in 3 days with solid tracking. Dissolved clean with zero cloudiness. Legit quality and will definitely be reordering.”

Sonia
Prince George, BC

★★★★★

“Paid with e-transfer and got the shipping notification the same afternoon. Packaging was completely plain which I appreciated. The product is working exactly as expected in my routine. 10/10.”

Daniel
Caledon, Ontario

★★★★★

“Great experience overall. The Reta itself seems super high grade. Took one extra day to get out to Calgary because of a weekend, but support was quick to reply to my email.”

Baldeep
Calgary, Alberta

★★★★★

“Nobody sells this locally and every other site charges out the a**. Found these guys, paid with e-transfer, and had the product at my door in 2 days. Dissolved clean and didn’t get killed on price. Definitely ordering again.”

Ali
Vancouver, BC

Additional information

Size (MG)

10mg, 20mg, 30mg

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