Melanotan 2 (10mg)

Description

Melanotan 2 – Synthetic Cyclic Melanocortin Receptor Agonist

Buy Melanotan 2 in Canada – Analytical Standard for MC1R/MC4R Signaling & Melanogenesis Research

Melanotan 2 (MT-2 / Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10] -MSH 4-10-NH2) is an engineered cyclic heptapeptide derivative of natural MSH developed to optimize biological half-life and enzymatic stability. By incorporating a cyclic lactam bridge, the peptide resists rapid enzymatic degradation and exhibits high binding affinity across multiple melanocortin receptor subtypes. In cellular models, MT-2 binds to dermal MC1R to drive cyclic adenosine monophosphate (cAMP) upregulation and microphthalmia-associated transcription factor (MITF) activation, resulting in eumelanin synthesis. Furthermore, its ability to cross the blood-brain barrier facilitates central research into hypothalamic MC3R and MC4R metabolic and autonomic signaling pathways. For Canadian research institutions and analytical laboratories investigating photobiology, receptor cross-talk, and peptide pharmacokinetics, North Vital Labs supplies analytical-grade Melanotan 2 backed by independent third-party verification.

Primary Research Applications

• MC1R Binding & Eumelanin Synthesis: Serves as a standard molecular benchmark for measuring intracellular cAMP accumulation, tyrosinase enzyme activation, and melanogenesis kinetics in melanocyte cell lines.

• Photobiology & UV Photoprotection Models: Facilitates laboratory study into cellular defense mechanisms, DNA repair signaling, and reduced apoptosis in UV-irradiated dermal models.

• Central Melanocortin Signaling (MC3R/MC4R): Widely utilized to evaluate hypothalamic neurocircuitry, food intake modulation, energy expenditure regulation, and central sympathetic outflow.

• Cyclic Peptide Enzymatic Stability: Enables comparative degradation and pharmacodynamic studies evaluating cyclic lactam configurations against native linear peptide structures.

Why Canadian Researchers Choose North Vital Labs

• 100% Domestic Canadian Fulfillment: Shipments originate directly within Canada, guaranteeing zero customs hold-ups, border seizures, or unexpected import tariffs.

• HPLC Lab-Verified Purity: Each production lot undergoes rigorous independent testing to ensure 99%+ chemical purity, complete with verifiable Certificates of Analysis (COAs).

• Direct Domestic Checkout: Seamless ordering supported by established Canadian payment methods, including Interac e-Transfer.

• Discreet Express Delivery: Shipped across Canada in protective, temperature-stable packaging with live tracking provided upon dispatch.

Compound Specifications

• Molecular Name: Melanotan 2 (MT-2 / Ac-cyclo[Nle4, Asp5, D-Phe7, Lys10] $\alpha$-MSH 4-10-NH2)

• Form: Lyophilized white powder (freeze-dried cake)

• Purity: 99%+ (HPLC lab-verified)

• Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).

• Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, cosmetic, clinical, or veterinary applications. This compound has not been evaluated or approved by Health Canada.