HMG (75iu)

Description

HMG 75 IU – Dual-Action Gonadotropin Complex Standard

Buy HMG in Canada – High-Purity Reference Standard for Dual FSHR & LHCGR Research

Human Menopausal Gonadotropin (HMG / Menotropin) is a specialized glycoprotein preparation providing balanced dual-gonadotropic activity. While standard LH or HCG molecules target only the LHCGR pathway, HMG delivers simultaneous agonism at both the follicle-stimulating hormone receptor (FSHR) and the luteinizing hormone receptor (LHCGR). In laboratory gametogenesis and steroidogenesis models, the FSH component selectively activates G$\alpha_s$-coupled adenylyl cyclase cascades in Sertoli cells (inducing androgen-binding protein transcription and promoting spermatogenesis) and ovarian granulosa cells (stimulating aromatase expression). Simultaneously, the LH component acts on Leydig or theca cells to drive de novo steroid synthesis. For Canadian academic institutions and analytical facilities investigating multi-receptor gonadotropic dynamics, germ cell maturation, and neuroendocrine axis preservation, North Vital Labs supplies analytical-grade HMG 75 IU backed by comprehensive third-party testing.

Primary Research Applications

• Concurrent FSHR & LHCGR Agonism: Serves as an analytical tool to evaluate cooperative dual-receptor signaling, intracellular cyclic AMP ($cAMP$) accumulation, and PKA phosphorylation cascades.

• Spermatogenesis & Sertoli Cell Function: Facilitates laboratory evaluation of androgen-binding protein (ABP) synthesis, blood-testis barrier integrity, and germ cell proliferation in testicular models.

• Follicular Recruitment & Granulosa Cell Aromatization: Enables controlled observation of follicular development, estrogen biosynthesis pathways, and granulosa-theca cellular cooperativity.

• Gonadotropin Receptor Downregulation Kinetics: Widely utilized in receptor desensitization and internalization assays to analyze the comparative feedback of balanced FSH/LH exposure versus isolated LH/HCG signaling.

Why Canadian Researchers Choose North Vital Labs

• 100% Domestic Canadian Fulfillment: Shipments originate directly within Canada, guaranteeing zero customs hold-ups, border clearance delays, or unexpected import tariffs.

• HPLC Lab-Verified Purity: Each lot undergoes rigorous third-party analytical testing to confirm 99%+ purity and verified 75 IU potency ratios, accompanied by accessible Certificates of Analysis (COAs).

• Direct Domestic Checkout: Seamless ordering supported by established Canadian payment methods, including Interac e-Transfer.

• Discreet Express Delivery: Shipped across Canada in protective, temperature-stable packaging with live tracking provided upon dispatch.

Compound Specifications

• Molecular Name: Human Menopausal Gonadotropin (HMG / Menotropin Complex)

• Potency / Quantity: 75 IU per vial (balanced FSH/LH activity)

• Form: Lyophilized white powder (freeze-dried cake)

• Purity: 99%+ (HPLC lab-verified)

• Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).

• Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, clinical, or veterinary applications. This compound has not been evaluated or approved by Health Canada.