IGF-1 LR3

Description

IGF-1 LR3 – Long-Acting Insulin-Like Growth Factor-1 Analogue

Buy IGF-1 LR3 in Canada – High-Purity Standard for IGF-1R Signaling & Myogenesis Research

IGF-1 LR3 is an engineered recombinant peptide derivative of human IGF-1 designed to optimize bioavailability and experimental longevity in cellular studies. By incorporating a 13-amino acid extension peptide at the N-terminus and replacing glutamic acid with arginine at position 3, the molecule exhibits an exceptionally low affinity for circulating IGF-binding proteins (IGFBPs). Consequently, the compound remains unbound and biologically available in culture media, facilitating prolonged binding to the transmembrane receptor tyrosine kinase $IGF\text{-}1R$. For Canadian academic institutions and analytical facilities investigating cellular hypertrophy, glucose uptake cascades, and cell cycle progression, North Vital Labs supplies analytical-grade IGF-1 LR3 backed by independent laboratory testing.

Primary Research Applications

• IGF-1R & Tyrosine Kinase Activation: Serves as a standard molecular tool to evaluate receptor auto-phosphorylation, IRS-1 docking, and downstream intracellular signaling cascades.

• PI3K/Akt/mTOR Pathway Dynamics: Facilitates controlled investigation into translational initiation, protein synthesis acceleration, and anti-apoptotic signaling mechanisms.

• Myoblast Proliferation & Differentiation: Widely utilized in skeletal muscle cell models to observe satellite cell activation, myoblast fusion, and myotube hypertrophy.

• Non-Insulin Glucose Transport: Enables laboratory study of glucose transporter translocation (GLUT4) and amino acid uptake kinetics independent of native insulin signaling.

Why Canadian Researchers Choose North Vital Labs

• 100% Domestic Canadian Fulfillment: Shipments dispatch directly within Canada, guaranteeing zero customs hold-ups, import tariffs, or border delays.

• HPLC Lab-Verified Purity: Each lot undergoes independent analytical testing to ensure 99%+ chemical purity, accompanied by verifiable Certificates of Analysis (COAs).

• Direct Domestic Checkout: Seamless ordering supported by established Canadian payment methods, including Interac e-Transfer.

• Discreet Express Delivery: Shipped across Canada in protective, temperature-stable packaging with live tracking provided upon dispatch.

Compound Specifications

• Molecular Name: Long $R^3$ IGF-1 (Long Arg3 Insulin-like Growth Factor-1)

• Form: Lyophilized white powder (freeze-dried cake)

• Purity: 99%+ (HPLC lab-verified)

• Storage Protocol: Store lyophilized powder in a cool, dry place shielded from direct light (refrigerate at 2°C–8°C once reconstituted).

• Compliance Statement: Exclusively intended for laboratory research and in vitro/in vivo scientific evaluation. Not for human, clinical, or veterinary use. This compound has not been evaluated or approved by Health Canada.